This book provides a scientific discussion on the pathogenesis of diabetes, the impairment of pancreatic beta cell function, and the protection and repair of pancreatic cells. It presents numerous clinical cases where diabetes patients have experienced varying degrees of reversal or relief. The discussion encompasses pharmacological therapy, dietary therapy, exercise therapy, and metabolic surgical interventions, collectively referred to as advanced, scientific, and systematic approach to comprehensive diabetes therapies. This book aims to deepen the public understanding of diabetes, raise awareness for vigilance and prevention, and bolster patients’ confidence in overcoming the disease. It encourages early control and potential reversal or relief, emphasizing the importance of early prevention, early detection, and early treatment. With this approach, diabetes patients can fully enjoy a high quality of life and achieve health and longevity.